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    Clinical Outcome Assessments

    What are Clinical Outcome Assessments (COAs)? What do they measure?

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    7,000+ COAs described in details and accessible in this unique database

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    Mapi Research Trust provides turnkey solutions for your Clinical Outcome Assessments (COAs) strategies - including COA databases, targeted literature reviews, licensing.

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    About us

    Mapi Research Trust is a non-profit organization dedicated to improving patients’ quality of life by facilitating access to Clinical Outcome Assessments(COAs).

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    A global team of multi-disciplinary experts

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    Collecting & Processing Patient Centered Outcomes information for more than two decades

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  4. Dermatology-Plastic Surgery

Dermatology-Plastic Surgery

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Articles

  • 2019. D’Angelo SP et al. – Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma.
  • 2018. Bharmal M et al. – Comparative effectiveness of avelumab versus chemotherapy in Merkel cell carcinoma: Innovative use of patient insights
  • 2018. Kaufman HL et al. – Living with Merkel cell carcinoma (MCC): Development of a conceptual model of MCC based on patient experiences
  • 2018. Bharmal M et al. – How to address the challenges of evaluating treatment benefits-risks in rare diseases? A convergent mixed methods approach applied within a Merkel cell carcinoma phase 2 clinical trial.
  • 2018. Kaufman HL et al. – Nonprogression with avelumab treatment associated with gains in quality of life in metastatic Merkel cell carcinoma
  • 2017. Bharmal M et al. – Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma
  • 2017. Mohr PM et al. – Real world treatment patterns and outcomes among metastatic cutaneous melanoma patients treated with ipilimumab
  • 2017. McArthur et al. – Health care resource utilization and associated costs among metastatic cutaneous melanoma patients treated with Ipilimumab (INTUITION Study)
  • 2017. Brengard-Bresler T et al. – Postoperative quality of life of patients with a bacterial necrotizing dermis-hypodermitis or necrotizing fasciitis, a ten-year study
  • 2016. Svedbom A et al. – Economic burden of psoriasis and potential cost offsets with biologic treatment: A Swedish register analysis
  • 2015. Svedbom A et al. – Increased cause-specific mortality in patients with mild and severe psoriasis: A population-based Swedish register study
  • 2015. Gilet H et al. – Development and psychometric validation of the REFlective evaLuation of psoriasis Efficacy of Treatment and Severity (REFLETS) questionnaire: A common measure of plaque-type psoriasis severity and treatment efficacy for patients and clinicians
  • 2015. Svedbom A et al. – Treatment patterns with topicals, traditional systemics and biologics in psoriasis – A Swedish database analysis
  • 2012. Dequen et al. – Systematic review and network meta-analysis of overall survival comparing 3 mg/kg ipilimumab with alternative therapies in the management of pretreated patients with unresectable stage III or IV melanoma
  • 2011. Van de Kerkhof et al. – Mixed treatment comparison of a two-compound formulation (TCF) product containing calcipotriol and betamethasone dipropionate with other topical treatments in psoriasis vulgaris

Posters & Presentations

  • 2017. ESMO Immuno-Oncology Congress – Health-Related Quality of Life (HRQoL) in Patients (Pts) With Merkel Cell Carcinoma (MCC) Receiving Avelumab (81P)
  • 2017. ISPOR European Congress – Minimal Impact on Patients’ Health Utilities Associated with Adverse Events in Metastatic Merkel Cell Carcinoma Patients on Treatment with Avelumab
  • 2017. ISPOR European Congress – Development of a tool to quantify an individual’s history of sun exposure: Qualitative phase of the development of the Sun Exposure Questionnaire
  • 2017. ISPOR European Meeting – Cost-effectiveness of nivolumab in combination with ipilimumab in first-line treatment of advanced melanoma in three European countries using 28-month overall survival from CheckMate 067
  • 2017. ISPOR European Congress – Using convergent mixed methods to evaluate treatment risks and benefits in rare disease: An example from a Phase II registration trial in metastatic Merkel Cell Carcinoma
  • 2017. ISPOR European Congress – Cost of nivolumab in combination with ipilimumab as first line treatment in advanced melanoma across various European markets
  • 2017. EADV Congress – French translation of the Simplified Psoriasis Index
  • 2017. ASCO Annual Meeting – Non-progression during avelumab treatment is associated with clinically relevant improvements in health-related quality of life in patients with Merkel Cell Carcinoma
  • 2017. ASCO Annual Meeting – Patient experiences with avelumab vs chemotherapy for treating Merkel Cell Carcinoma: Results from protocol-specified qualitative research
  • 2017. ISPOR Annual International Meeting – Psychometric validation of the FACT-M questionnaire in patients with Merkel Cell Carcinoma
  • 2017. ISPOR Annual International Meeting – Non-progression on treatment with avelumab contributed to gains in health utility scores with metastatic Merkel Cell Carcinoma
  • 2017. AEDV – Congreso Nacional de Dermatologia y Venereologia – Cost-effectiveness of ixekizumab vs. secukinumab in the treatment of moderate to severe plaque psoriasis in Spain
  • 2016. ISPOR European Congress – Budget impact of apremilast for moderate to severe plaque psoriasis in the UK
  • 2016. ISPOR European Congress – Cost-effectiveness of apremilast in moderate to severe psoriasis in Canada
  • 2016. ISPOR European Congress – Cost-effectiveness analysis of ixekizumab vs. secukinumab in sequential biologic treatment of psoriasis in the UK
  • 2015. ISPOR Annual European Congress – Cost-Effectiveness of Apremilast in Moderate to Severe Psoriasis in Scotland
  • 2015. ISPOR Annual European Congress – Does Health-Related Quality of Life Evaluation in Psoriasis Matter? A Review of Labels of Psoriasis Products Approved by the FDA and the EMA
  • 2014. ISPOR Annual European Congress – Assessing the Relationship Between Treatment Effect and Baseline Risk in Network Meta-Analysis of Moderate to Severe Chronic Plaque Psoriasis Trials
  • 2014. ISPOR Annual International Meeting – Comparability of Trial Populations in Network Meta-Analyses Assessing Biologic Treatments in Moderate to Severe Plaque Psoriasis
  • 2013. European Academy of Dermatology and Venereology (EADV) Congress – Finalisation and psychometric validation of the REFlective evaLuation of psoriasis Efficacy of Treatment and Severity (REFLETS) questionnaire
  • 2012. ISPOR European Congress – Efficacy of Ceftaroline Fosamil and Other Intravenous Antibiotics in the Treatment of Complicated Skin and Soft Tissue Infections (CSSTI): A Network Meta-Analysis (NMA)
  • 2012. ISPOR Annual International Meeting – Psychometric Validation of the Tummy Tuck Questionnaire
  • 2012. Infectious Disease Research Network. Primary Care Database Symposium – The use of GP questionnaires to assess psoriasis severity in The Health Improvement Network (THIN) database
  • 2011. ISOQOL Annual Conference – Content Assessment of the Facial Line Outcomes (FLO-11) Questionnaire
  • 2011. European Academy of Dermatology and Venereology (EADV) Congress – Development of a unique tool reflecting patient and physician perceptions of psoriasis severity and treatment efficacy
  • 2011. ISPOR Annual International Meeting – Gap Analysis for Patient-Reported Outcomes Measures for Alopecia
  • 2010. ISPOR European Congress – Development of an Instrument Mirroring Patient and Physician Perception of Psoriasis Severity and Treatment Effect
  • 2010. ISPOR Annual International Meeting – Comparison of the PRO Endpoints found in Labeling Claims of Products for the Treatment of Psoriasis with Those Recommended by the Corresponding EMA Guidance
  • 2008. ISPOR European Congress – A Disease Model Illustrating the Impact of Psoriasis on Patients’ Lives
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